Gamma Hydroxybutyrate (GHB) is scheduled as:

• A. Schedule I
• B. Schedule II
• C. Schedule IV
• D. Schedule III

Answer: (D)

GHB itself is a Schedule I controlled substance, because it has no accepted medical use in the United States and carries a high potential for abuse. The only exception is the pharmaceutical salt form, sodium oxybate (the active ingredient in Xyrem), which is a Schedule III substance due to its medical use for narcolepsy and the controlled distribution program surrounding it. So, when the question refers to GHB generally, the correct classification is Schedule I; the Schedule III designation only applies to the medically approved salt form, not to GHB as a standalone compound.