Which drug is Schedule II - depressant?

• A. Pentobarbital
• B. Levorphanol
• C. Meperidine
• D. Morphine

Answer: (A)

Scheduling CNS depressants hinges on their potential for abuse and their accepted medical use. Drugs in Schedule II have medical use but high abuse potential and require strict controls, like limited prescriptions and no refills.

Pentobarbital is a barbiturate CNS depressant with a well-established medical use, but it carries a high risk of abuse and dependence. Because of that balance of medical utility with significant abuse potential, it is classified as Schedule II. The other options listed are also controlled substances, including opioids, which are typically Schedule II as well, but pentobarbital is a classic example of a Schedule II depressant due to its barbiturate nature and history of misuse.