Which vaccine may be administered by an RPh without a collaborative agreement?

• A. PCV, Td over 18 years
• B. Zoster vaccine over 60 years
• C. Epi or Benadryl for adverse events over 12 years
• D. Influenza vaccines for patients over 12 years

Answer: (D)

Pharmacists can vaccinate under state law, but the level of oversight needed (whether a collaborative agreement is required) varies by vaccine. The influenza vaccine is specifically allowed for pharmacists to administer to patients 12 years and older without a collaborative agreement in many jurisdictions, as part of expanding access to a high-priority public health intervention.

This is why the influenza vaccine for patients over 12 is the best choice: it falls under autonomous pharmacist immunization authority, making it permissible without a collaborative agreement. The other items either involve vaccines that typically require physician collaboration or oversight, or they are not vaccines at all (epinephrine or diphenhydramine are treatments for adverse events, not vaccines).